New research from BYU on Alzheimer’s Disease shows ‘lifestyle origin at least in some degree’

For years, research to pin down the underlying cause of Alzheimer’s Disease has been focused on plaque found to be building up in the brain in AD patients. But treatments targeted at breaking down that buildup have been ineffective in restoring cognitive function, suggesting that the buildup may be a side effect of AD and not the cause itself. A new study from a team of BYU researchers finds novel cellular-level support for an alternate theory that is growing in strength: Alzheimer’s could actually be a result of metabolic dysfunction in the brain. In other words, there is growing evidence that diet and lifestyle are at the heart of Alzheimer’s Disease. “Alzheimer’s Disease is increasingly being referred to as insulin resistance of the brain or Type 3 Diabetes,” said senior study author Benjamin Bikman, a professor of physiology and developmental biology at BYU. “Our research shows there is likely a lifestyle origin to the disease, at least to some degree.” For the new study, published in academic journal Alzheimer’s & Dementia, the BYU research team examined RNA sequences in 240 post-mortem Alzheimer’s Disease-impacted brains. They were looking specifically at the gene expression of nervous system support cells during two types of … Continue reading New research from BYU on Alzheimer’s Disease shows ‘lifestyle origin at least in some degree’